Brittany MacTaggart

Postdoctoral Fellow

I am a cell biologist, who is generally interested in how post-translational modifications of cytoskeletal proteins affect their dynamics in cells. In 2024, I earned my PhD in Cell and Molecular Biology from the University of Pennsylvania in Dr. Anna Kashina’s lab, where I studied the post-translational modification arginylation and its role in maintaining microtubule dynamics. Now, as a postdoctoral researcher in Dr. Duncan Clarke’s lab, I am studying a metaphase checkpoint that is activated when Topoisomerase II remains trapped on DNA. Specifically, I am investigating the involvement of Aurora B kinase, which ensures that kinetochores are properly attached to spindle microtubules during mitosis. My goal is to continue teaching students in the classroom and lab by becoming a professor at a primarily undergraduate institution. Outside of the university, I am also very passionate about providing science education to incarcerated students. Science is for everyone!

Brittany MacTaggart